NIH Releases Request for Information on Maximizing Research Funds by Limiting Allowable Publication Costs   

To maximize the value of NIH research grants, grantees should aim to utilize as much of their funds as possible for research activities. With this in mind, NIH has released a request for information (RFI) regarding policy options to maximize research funds by limiting allowable publication costs (APCs).   

Stakeholders are invited to provide feedback on the policy options described in the RFI. Comments must be submitted electronically to https://osp.od.nih.gov/comment-form-maximizing-research-funds-by-limiting-allowable-publishing-costs.  Responses will be accepted through September 15, 2025

Context on this issue can be found in a statement previously issued by NIH Director, Dr. Jay Bhattacharya. Also, for additional information, please see the latest Under the Poliscope blog from Dr. Lyric Jorgenson.

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Academic Freedom, Evidence-Based Policy, and the True Cost of Scientific Publishing

You may have recently heard the NIH Director speak about the importance of academic freedom in scientific discovery. In short, NIH defines academic freedom as the ability to engage in open, rigorous discourse to stress test ideas, challenge the status quo, and shape the most impactful path forward.

Now, I might be biased – but I believe that nowhere is academic freedom more vital than in the policymaking process. For a policy to have its intended impact – with minimized unintended consequences – policymakers must rigorously debate the merits of the evidence, evolving societal and ethical views, the practicalities of implementation, etc. Public debate is the cornerstone of sound policy.

For these reasons, I’m extremely proud to say NIH continues to value public debate around our newest policy proposal regarding maximizing research funds by limiting allowable publication costs.

Let’s start with the basics: To get science into the hands of other scientists, practitioners, and the public, we rely on a system of dissemination – namely, peer-reviewed publication. Ensuring that published research is rigorous, reliable, and compliant with federal policy requirements comes at a cost. Historically, NIH has supported these costs as part of its mission to advance science.

On the flip side, we often hear a valid concern: the public pays for everything – from research infrastructure to the research project, to the data sharing, to the publication – and ultimately, for access to any resulting product. This raises a fundamental question:

What is a reasonable cost for publication?

It is increasingly clear that some current practices potentially divert resources, and the NIH budget is a zero-sum game. What is the appropriate tradeoff between a publication cost and seeding the next groundbreaking discovery or promising early-career investigator? In asking ourselves this question, our policy goals remain consistent:

  • Incentivize rigorous, unbiased scientific review
  • Maximize the impact of NIH research dollars to support transformative discoveries

To make a truly fair system, we need your help to figure this out. Share your thoughts, concerns, or ideas on how we can strike the right balance between dissemination, fiscal responsibility, and scientific integrity. Submit your comments here by September 15, 2025: https://osp.od.nih.gov/comment-form-maximizing-research-funds-by-limiting-allowable-publishing-costs/

Lyric Jorgenson, PhD
NIH Associate Director for Science Policy
About Lyric

NIH Issues Policy to Support Originality and Fairness in Research Application Process

The use of Artificial Intelligence (AI) tools can be helpful in limited aspects of preparing NIH research applications.  However, it is critical to maintain the fairness and originality of NIH’s research application process. The rapid submission of large numbers of research applications from a single Principal Investigator (PI) may also unfairly strain NIH’s application review processes. 

With this in mind, NIH is issuing a policy to outline guidance for appropriate usage of AI in research applications. To support this goal, NIH is also limiting the number of applications that NIH will consider per PI per calendar year.  

Full policy information can be found at: https://grants.nih.gov/grants/guide/notice-files/NOT-OD-25-132.html. Questions may be sent to [email protected].  

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NIH Public Access Policy Mandating Zero Embargo Now in Effect

Effective today, the NIH Public Access Policy is in effect and manuscripts accepted for publication in a journal on or after July 1, 2025, must be submitted to PubMed Central for public availability without embargo upon the official date of publication.

To assist with compliance, NIH has developed a new website dedicated to the Public Access Policy which includes an overview of the policy, supplemental guidance, tips for submitting to PubMed Central, contact information, and FAQs.  The site can be found at: https://grants.nih.gov/policy-and-compliance/policy-topics/public-access.

Questions can be sent to [email protected].