…the generation of reassortant viruses with phenotypic properties of concern. GoF RBA Report Gryphon Scientific, LLC 8 2 Overview and Purpose The overarching purpose of conducting the risk/benefit analysis (RBA)…

…overall aim of the framework is to provide guidance to the NIH, who will be directing Gryphon Scientific in conducting the RBA. In order for the RBA to be credible,…

…overall aim of the framework is to provide guidance to the NIH, who will be directing Gryphon Scientific in conducting the RBA. In order for the RBA to be credible,…

…Analysis (RBA) of Gain of Function Research�Summary Overall Approach to the RBA A Note on Interpreting Our Results Overall Approach to the RBA Interplay of Components of Biosafety RA Using…

…Scientific RBA of GOF Research Rocco Casagrande, Ph.D., Principal Investigator (PI), Managing Director, Gryphon Scientific Dr. Casagrande summarized the purpose and scope of the RBA, noting that the biosafety risks…

…that encompassed both benign and worrisome aspects of a broader range of GOF studies than those that have raised concerns. The RBA analyzed biosafety and biosecurity risks as well as…

…regarding the funding and conduct of GOFR. RBA Limitations While the commissioned RBA will be valuable in all of these ways—and despite expectation that the RBA will be so thorough,…

…and conduct of GOFR. RISK-BENEFIT ASSESSMENT LIMITATIONS While the commissioned RBA will be valuable in all of these ways—and despite expectation that the RBA will be so thorough, by evaluating…

…to guide NIH as it manages Gryphon Scientific in conducting the RBA. The framework outlines the principles to guide the RBA, describes the risks and benefits to analyze, and recommends…

…c ha ng e ac co rd in gl y. © 20 13 L an de s B io sc ie nc e. D o no t d is tri…