…the generation of reassortant viruses with phenotypic properties of concern. GoF RBA Report Gryphon Scientific, LLC 8 2 Overview and Purpose The overarching purpose of conducting the risk/benefit analysis (RBA)…

…c ha ng e ac co rd in gl y. © 20 13 L an de s B io sc ie nc e. D o no t d is tri…

…c ha ng e ac co rd in gl y. © 20 13 L an de s B io sc ie nc e. D o no t d is tri…

…that encompassed both benign and worrisome aspects of a broader range of GOF studies than those that have raised concerns. The RBA analyzed biosafety and biosecurity risks as well as…

…and conduct of GOFR. RISK-BENEFIT ASSESSMENT LIMITATIONS While the commissioned RBA will be valuable in all of these ways—and despite expectation that the RBA will be so thorough, by evaluating…

…and should not be considered to be official NSABB 18 findings or recommendations to the U.S. government. This document does not represent official policy 19 of the U.S. government. 20…

…that should be required in order for certain GOF studies to be safely conducted? Points 1. NSABB dra@’s GOF of concern focus is appropriate 2. RBA significantly underesOmates risks of…

…obtain additional input to aid its RBA efforts. IDSA strongly supports these actions, and also urges the NSABB and Gryphon Scientific to consider seeking additional perspectives to inform the RBA…

…obtain additional input to aid its RBA efforts. IDSA strongly supports these actions, and also urges the NSABB and Gryphon Scientific to consider seeking additional perspectives to inform the RBA…

…THE RISK AND BENEFIT ASSESSMENTS (RBA) NSABB approved its Framework to guide the RBA in May 2015. The Framework recommended a number of features and principles to guide the development…