Health Care Research Policy

Comparative Effectiveness Research

NIH’s comparative effectiveness research (CER) portfolio encompasses studies comparing different interventions and strategies to prevent, diagnose, treat, and monitor diseases and conditions in real-word settings. A key area of health services research, CER generates knowledge about which interventions are most effective for which patients under specific circumstances. The Health Care Research Policy Program identifies, analyzes, and develops policy proposals and recommendations that promote opportunities for co-funding CER between NIH and other key organizations with robust comparative effectiveness research portfolios; scientifically rigorous collection and interpretation of patient-reported outcomes; and increasing the use of common data elements to enhance pragmatic clinical and observational trials.